A 6-year-old girl was brought to her pediatrician for vaginal bleeding. Her parents noticed a recent enlargement of her breast tissue and were concerned that she might be experiencing very early onset of puberty. She also had a number of brown, hyperpigmented café-au-lait patches on her cheeks, back, and trunk. The girl had always been noticeably different from her peers and they thought this change might lead to teasing at school.
Can you diagnose this patient? Use the differential builder in VisualDx.
B. McCune-Albright syndrome
C. Functional ovarian tumor
D. Cushing syndrome
See the next page for the answer.