Clinical

Articles

An imaging study of girls with idiopathic CPP and matched controls suggests idiopathic CPP was associated with increased gray matter and white matter volumes in the cerebral area. 

Study Assesses Brain Volume Differences in Girls with Central Precocious Puberty

Using data from more than 50 women, investigators determined exposure to GnRHa treatment was not associated with an increased risk of developing PCOS in women with CPP treated with GnRHa. 

GnRHa Not Associated with Increased PCOS Risk in Patients with Endocrine Disorders

Results of a recent study provide insight into the prevalence of rare sequence variants among the MKRN3, DLK1, KISS1, and KISS1R genes in children with CPP. 

Study Details Prevalence of Genetic Variants in Central Precocious Puberty

Mount Sinai-led chart review provides insight into the influence of various factors on time to menarche among girls with central precocious puberty who received GnRHa treatment. 

Study Details Factors Negatively Impacting Time to Menarche in Central Precocious Puberty

A cross-sectional study has returned results that suggest a risk score model could help identify patients with central precocious puberty without the need for more expensive and invasive stimulation tests.

Risk Score Model Could Provide Inexpensive CPP Diagnosis Tool

A systematic review and meta-analysis detail the effects of GnRHa therapy on final adult height, BMI, risk of PCOS, and more long-term outcomes among patients with idiopathic CPP. 

Influence of GnRHa on Long-Term Outcomes in Idiopathic Central Precocious Puberty

Patrick Campbell is the assistant managing editor of Endocrinology Network, as well as its sister publication Practical Cardiology. Prior to joining these brands, he led coverage of cardiology and diabetes with HCPLive. Before joining parent company MJH Life Sciences in 2019, he spent time as a beat reporter with the Pocono Record in Stroudsburg, PA, and Star News Group in Manasquan, NJ. He also touts experience in multimedia, having spent time as a freelance multimedia specialist with NJ Advance Media and multimedia coordinator at the Pocono Record.  Follow him on Twitter @RealPatCampbell or reach him via email at PCampbell@mjhlifesciences.com.

A study assessing levels of flourine in cosmetic products available in the US and Canada suggests many of these products could contain levels of chemicals that, over time, could cause harm. 

Study Details "Widespread" Use of Endocrine-Disrupting Chemicals in North American Cosmetic Products

A study from Canada is calling for additional attention to paid to the screening, diagnosis, and treatment of primary aldosteronism in adult patients.  

Study Underlines Low Rates of Screening, Treatment for Primary Aldosteronism

An analysis of data from the Veterans Health Administration is providing insight into the apparent increase in risk of fracture or osteoporosis among older adults with kidney or ureteral stones.

Study Links Kidney Stones to Fracture Risk in Older Adults

Results of a two-sample Mendelian randomization analysis suggest vitamin D levels were unlikely to have a large effect on a person's risk for developing type 1 diabetes. 

Endocrine Diseases