Weight Management

The Endocrinology Network® Weight Management clinical resource center is the home of all content related to weight loss and obesity management. Now a full-blown epidemic, the obesity crisis is one of the most prominent and dangerous health crises in the US. This page will provide insight and perspective related to FDA approvals, the latest studies, and guideline updates related to nutrition, obesity, and weight management.

'Metabolically Healthy' Obesity Still Puts Patients at Increased Risk of Adverse Health Outcomes

June 14, 2021

Data from the UK Biobank cohort details the increased risk of adverse health outcomes, including the development of diabetes and heart failure, among patients considered to have metabolically healthy obesity.

Study Suggests 2 Servings of Fruit Per Day Cuts Odds of Developing Diabetes by 36%

June 06, 2021

An analysis of food frequency questionnaire and biomarker data from more than 7000 adults indicates consumption of 2 or more servings of whole fruit per day was associated with 36% lower odds of developing diabetes in the next half-decade.

Semaglutide (Wegovy) Approved for Chronic Weight Management in Patients with Obesity or Overweight

June 04, 2021

The FDA has announced the approval of semaglutide 2.4 mg (Wegovy) for chronic weight management in patients with obesity or overweight—the first drug to receive such an approval from the FDA in more than half a decade.

USPSTF Issues Recommendation on Interventions for Healthy Weight Gain During Pregnancy

May 25, 2021

The USPSTF has issued the organization's first recommendation on interventions for promoting healthy weight gain during pregnancy and also provided an overview of the evidence base used for the recommendation statement.

Single-Arm Study Finds Very-Low Calorie Ketogenic Diet Could Improve Testosterone Levels in Men

May 24, 2021

A single-arm study examining the effects of a very-low calorie ketogenic diet over a 1-month period indicates the dietary approach was associated with improvements in body weight and sex hormones among men with overweight or obesity.

Rising Obesity Rates Have Had Similar Impact on Progress Against Cardiovascular Disease and Cancer

May 18, 2021

A comparison of annual mortality rates related to cancer and cardiovascular disease is shedding light on the impact of the obesity epidemic on progress against both since 1999.

Subcutaneous Semaglutide Suppresses Appetite, Reduces Excess Energy Intake in Patients with Obesity

May 13, 2021

A new phase 1 trial presented at ECO 2021 demonstrates the impact of semaglutide on appetite and body weight in patients with obesity, indicating use of the GLP-1 RA reduced energy intake 35% and resulted in a nearly 10% reduction in body weight over 20 weeks.