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Cushing's Syndrome


The Endocrinology Network® Cushing Disease clinical resource center is a hub for the latest in the management and diagnosis of Cushing’s syndrome. Often referred to as hypercortisolism, this page will host content including articles, videos, podcasts, and clinician-authored columns.

Mild Autonomous Cortisol Secretion Linked to Increased Hypertension, Requiring Insulin Therapy

January 06, 2022

A cross-sectional study of more than 1000 patients suggests presence of MACS in patients with benign adrenal tumors was associated with increased prevalence and severity of hypertension as well as an increase in the likelihood of requiring insulin therapy in type 2 diabetes.

Levoketoconazole (Recorlev) Receives FDA Approval for Endogenous Cushing's Syndrome

January 04, 2022

Announced on December 30, the approval of levoketoconazole (Recorlev), a cortisol synthesis inhibitor, is for the treatment of endogenous hypercortisolemia in adult patients with Cushing’s syndrome for whom surgery is not an option or has not been curative.