Our April list includes CV events with DPP-4 or SGLT2 inhibitors vs. insulin, and impact of obesity on nonalcoholic fatty liver disease and thyroid function.
We present a selection of interesting endocrinology articles for the month of April in the following slides. See the slide legends for links to the article summaries.
The Impact of Preoperative Thyroid Function on Weight Loss After Bariatric Surgery. Abstract link. **** Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Achieve Similar Early Improvements in Beta-Cell Function in Obese Patients with Type 2 Diabetes. Abstract link.
New-Onset Diabetes After Statin Exposure in Elderly Women: the Australian Longitudinal Study on Women’s Health. Abstract link. Fasting Pancreatic Polypeptide: a Novel Marker of Cardiovascular Risk and Coronary Artery Disease in Men with Type 2 Diabetes Mellitus. Abstract link.
Bacterial Resistance in Patients with Infected Diabetic Foot without Major Amputation Outcome in a Peruvian National Hospital. Abstract link. **** Pharmacotherapy for Diabetic Peripheral Neuropathy Pain and Quality of Life. Abstract link.
Diabetes Incidence and Glucose Intolerance Prevalence Increase with Higher Outdoor Temperature. Abstract link. **** Pathogenesis of Type 2 Diabetes in Obese Adolescents: Metabolites of Serotonin and Mitochondrial Function in 24-Hour Urine Samples. Abstract link.
Breaking up Prolonged Sitting Alters the Postprandial Plasma Lipidomic Profile of Adults with Type 2 Diabetes. Abstract link. **** Piloting a Remission Strategy in Type 2 Diabetes: Results of a Randomized Controlled Trial. Abstract link.
Linagliptin Exerts an Anti-Inflammatory Effect in Well Controlled Patients with Type 2 Diabetes. Abstract link. **** Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Insulin Glargine as Add-on to Metformin (with or without Sulfonylureas) in Insulin-Naive Patients with Type 2 Diabetes (SUSTAIN 4): a Randomised, Open-Label, Parallel-Group, Multicentre, Multinational, Phase 3a Trial. Abstract link.
Coadministration of Canagliflozin and Phentermine for Weight Management in Overweight and Obese Individuals without Diabetes: a Randomized Clinical Trial. Abstract link. **** Novel Oral Glucose-Lowering Drugs Are Associated with Lower Risk of All-Cause Mortality, Cardiovascular Events and Severe Hypoglycaemia Compared with Insulin in Patients with Type 2 Diabetes. Abstract link.
Post-Prandial Brain Response to High-Calorie Visual Food Cues Is Greater in Obese vs. Lean Children. Abstract link. **** Low Calorie Sweeteners Alter Glucose Uptake and Promote Adipogenesis in Human Fat Biopsy-Derived Mesenchymal Stromal Cells (MSCs) in-Vitro and in Subjects’ Subcutaneous Fat. Abstract link.
Skipping Breakfast and 5-Year Changes in Body Mass Index and Waist Circumference in Japanese Men and Women. Abstract link. **** Childhood Adiposity and Nonalcoholic Fatty Liver Disease in Adulthood. Abstract link.