Is the number of CV health measures associated with similar risk reduction among patients with higher T2DM risk or lower risk? New study sheds light.
Joshua Joseph, MD, and fellow researchers from multiple centers in the US have found that having a higher number of ideal cardiovascular health components is associated with lower risk of diabetes in patients with normal fasting glucose. Click through the slides below for details on their study and take home points for clinical practice.
Cardiovascular Health and Diabetes. Study authors sought to examine if achieving more optimal CVH measures is associated with similar risk reduction among those with higher baseline risk of T2DM (eg, IFG, African-American race) vs those with lower risk (eg, normal fasting glucose, white race).
The Study. Researchers analyzed data from the Reasons for Geographic and Racial Differences in Stroke study, a prospective national cohort study looking at community-dwelling adults to examine regional and racial influences on stroke mortality. Study included 7758 subjects with the primary exposure being ideal CVH, assessed using 6 baseline metrics. The number of ideal CVH metrics were categorized into 3 groups (poor, intermediate, and ideal) with the primary outcome being incident T2DM.
Take Home Points:
Perspective. "Very few diseases have a more profound impact on the entire human body than T2DM, placing it near the top of the clinician’s most dangerous villains list. The authors of this study highlight the importance of recognizing those who will benefit the most from targeted health goals and those who may require a different approach.”
Reference: Joseph JJ, Bennett A, Echouffo Tcheugui JB, et al. Ideal cardiovascular health, glycaemic status and incident type 2 diabetes mellitus: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study [published ahead of print January 15, 2019]. Diabetologia. doi: 10.1007/s00125-018-4792-y.