ENDO 2017: Sleep Studies

April 2, 2017

Studies presented at ENDO 2017 examined the impact of sleep disorders on gestational diabetes, bone formation, and adolescents with and without diabetes.

Studies presented at ENDO 2017 looked at a screening tool to identify sleep apnea risk in women with gestational diabetes, examined the impact of sleep restriction and circadian disruption on bone formation, and studied the impact and frequency of obstructive sleep apnea on obese adolescents with and without diabetes.

Obstructive Sleep Apnea in Gestational Diabetes: Prevalence, Predictive Factors and the Development of a Screening Tool. Abstract link.

Can a screening tool identify sleep apnea in women with gestational diabetes?

An algorithm using the Berlin questionnaire and neck circumference can help screen for obstructive sleep apnea in obese women with gestational diabetes.

Lower Bone Formation after 3 Weeks of Sleep Restriction with Circadian Disruption: a Mechanism for Sleep-Related Bone Loss. Abstract link.

Would a sleep and circadian disturbance negatively affect bone mineral density?

Three weeks of sleep loss and circadian disruption can result in an uncoupling of bone turnover, with decreased bone formation and unchanged bone resorption. Sleep disruption could be the most damaging to bone health during high bone turnover states.

Obstructive Sleep Apnea Risk in Obese Adolescents with and without Type 2 Diabetes: a Pilot Study. Abstract link.

What is the frequency and impact of obstructive sleep apnea (OSA) in obese adolescents with T2DM?

OSA frequency was similar between the groups, but severity of sleep-disordered breathing was higher with T2DM. Also, in adolescents without T2DM, “AHI associates with lower whole body insulin sensitivity, suggesting that [sleep disordered breathing] may play a role in the development of T2DM in childhood.”