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There are 10 FDA-approved DPP-4 inhibitors--single agents and combination products. Do you speak their language? Find out with these 5 questions.
Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have been in the type 2 diabetes tool box since 2006. They are associated with a modest decrease in A1c and a mostly neutral impact on weight. There are currently four approved agents in the US and there are also five approved agents that combine a DPP-4I with metformin and one that combines a DPP-4I and a thiazolidinedione.
How well versed are you in the language of DPP-4I? Find out in 5 short questions.
1. Which one of the following DPP-4I combination drugs does NOT contain metformin:
Answer: A. Tradjenta
Tradjenta is the DPP-4I linagliptin
2. The DPP-4I combination drug that contains a thiazolidinedione is:
Answer: C. Oseni
Oseni combines alogliptin and pioglitazone; Nesina is alogliptin; Trulicity is dulaglutide; Onglyza is saxagliptin
3.Kazano combines metformin with which of the following DPP-4Is?
Answer D. Alogliptin
4. Januvia is the brand name for which of the following generic DPP-4Is?
Answer: D. Sitagliptin
5. Jentadueto is the brand name for the combination of saxagliptin and metformin.
Anwer: B. False
Jentadueto is linagliptin and metformin
Table. DPP-4Is, DPP-4I Combinations, GLP-1 Receptor Agonists