Authors of a new study found that patients who develop diabetes later in life have a higher risk of cardiovascular disease.
Researchers led by Michael Bancks, PhD, assistant professor in the department of epidemiology and prevention at the Wake Forest School of Medicine in Winston-Salem, North Carolina, have determined that patients in whom diabetes develops in midlife have the highest long-term absolute risk for cardiovascular disease. Click through the slides for details on their study and take home points for clinical practice.
Diabetes and Cardiovascular Disease. The absolute risk of CVD in middle-aged patients with DM ranges from 49% to 67% in women and 62% to 78% in men. However, it is unknown what impact prediabetic elevated FG levels have on absolute CVD risk. Authors of this study sought to determine absolute 30-year risks for CVD by FG level and by 4-year change in FG level at midlife.
The Study. Authors utilized data from the Cardiovascular Disease Lifetime Risk Pooling Project which looked at cohorts that measured FG levels and had records of CVD outcomes (eg, CHD and stroke). Each patient was followed from study entry until occurrence of first CVD event, death, or they reached age 85. Risk estimates for CVD, CHD, and stroke calculated according to FG category and stratified by age and sex. The primary sample was 19 630 individuals (6197 black, 11 015 women) without prior CVD event at index age of 55 years.
Take Home Points:
Reference: Bancks MP, Ning H, Allen NB, et al. Long-term absolute risk for cardiovascular disease stratified by fasting glucose level [published ahead of print January 7, 2019]. Diabetes Care. doi: 10.2337/dc18-1773.