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Weight Management
The Endocrinology Network® Weight Management clinical resource center is the home of all content related to weight loss and obesity management. Now a full-blown epidemic, the obesity crisis is one of the most prominent and dangerous health crises in the US. This page will provide insight and perspective related to FDA approvals, the latest studies, and guideline updates related to nutrition, obesity, and weight management.
Eliminating Just 200 Calories Per Day Could Pay Major Dividends for Heart Health in Obesity
August 03, 2021
An ancillary study to the INFINITE trial details the benefits of caloric restriction plus exercise versus exercise alone on aortic stiffness measured using CMRI in older adults with obesity.
Bariatric Surgery Improves Long-Term Quality of Life, Health Perception in Patients with Uncontrolled T2D
July 27, 2021
An analysis of a subset of patients from the STAMPEDE trial provides new evidence detailing the quality of life improvements associated with undergoing bariatric surgery in patients with uncontrolled type 2 diabetes.
REDUCE-IT BMI: Icosapent Ethyl Provides Consistent Benefit, Regardless of BMI
June 28, 2021
Deepak Bhatt, MD, MPH, discusses the results of REDUCE-IT BMI, which examined effects of icosapent ethyl vs placebo based on baseline BMI, that he presented at ADA 2021.
ADA 2021 Deep Dive into Semaglutide 2.4 mg: A Turning Point for Obesity Management?
June 25, 2021
Ahead of ADA 2021, Dr. Thomas Wadden discusses the significance of the semaglutide 2.4 mg (Wegovy) approval for chronic weight management and Novo Nordisk's plans to evaluate an oral version.
UNC-Led Review Details Lack of High-Quality Evidence to Support Supplements, Alternative Therapies for Weight Loss
June 23, 2021
A look at more than 300 clinical trials examining dietary supplements and alternative therapies for inducing weight loss has returned evidence detailing a lack of high-quality evidence related to the efficacy of these approaches.
Early Life BMI Plays Role in Future Diabetes and CVD Risk, Regardless of Adult BMI
June 22, 2021
Using 24 years of follow-up data from more than 12k adolescents provides insight into the impact of childhood BMI z-scores on risk of adverse health outcomes, including development of diabetes and premature myocardial infarction, in adulthood.
Randomized Trial Suggests There is "Nothing Special" About Effects of Intermittent Fasting
June 17, 2021
A randomized trial comparing 3 dietary approaches, including 2 involving fasting, suggests the recently popularized approach does not provide any substantial benefits compared to a traditional diet.
Discussing Bariatric Surgery Linked to Increased Weight Loss Whether or Not Patients Undergo Surgery
June 15, 2021
A retrospective analysis of data from more than 30k patients with severe obesity suggests having a discussion about bariatric surgery with a clinician resulted in greater weight loss, regardless of if they underwent a bariatric procedure, but fewer than 9% had these discussions.
'Metabolically Healthy' Obesity Still Puts Patients at Increased Risk of Adverse Health Outcomes
June 14, 2021
Data from the UK Biobank cohort details the increased risk of adverse health outcomes, including the development of diabetes and heart failure, among patients considered to have metabolically healthy obesity.
Study Suggests 2 Servings of Fruit Per Day Cuts Odds of Developing Diabetes by 36%
June 06, 2021
An analysis of food frequency questionnaire and biomarker data from more than 7000 adults indicates consumption of 2 or more servings of whole fruit per day was associated with 36% lower odds of developing diabetes in the next half-decade.