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Endo News Roundup: Diabetes Biomarker

Endo News Roundup: Diabetes Biomarker

  • Endo News Roundup: Diabetes Biomarker
  • “Flash” Sensor Monitors Glucose Levels Abstract link.
  • A "flash" monitoring system shows good agreement with finger-stick blood glucose results in children and teens.
  • The “flash” glucose sensor, which does not require user calibration, may be suitable for a broad range of children and young people with diabetes.
  • Insulin Resistance Tied to Bone Turnover Abstract link.
  • Increased visceral adiposity and higher fasting insulin levels are associated with lower levels of bone turnover markers, adding understanding to the skeletal complications that result from improper control of diabetes.
  • Clinicians may need to take into account not only bone mineral density via routine scans, but also bone turnover marker levels for their T2DM patients.
  • Biomarker Helps Predict Diabetes Abstract link.
  • FGF21, a novel metabolic regulator of glucose and lipid metabolism and a potential therapeutic agent for metabolic disorders, could also be a useful biomarker for the prediction of incident diabetes.
  • As a single biomarker, FGF21 adds value to established risk factors when used in the construction of diabetes prediction models.
  • Clinical Implications

New studies in diabetes include: an alternative sensor-based method for glucose monitoring in children and young people with type 1 diabetes (T1DM) appears to be accurate and safe; insulin resistance is associated with lower bone turnover levels, which could be a factor in the higher fracture rates seen in diabetes; and serum fibroblast growth factor 21 (FGF21) appears to be a good biomarker for diabetes prediction, and could be considered as an alternative to the oral glucose tolerance test (OGTT).

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